Gliclazide 80mg + Metformin HCL 500mg is a combination medication used to manage type 2 diabetes mellitus.

Gliclazide (80mg) is a sulfonylurea that works by stimulating the pancreas to release more insulin in response to elevated blood glucose levels. This helps lower blood sugar levels after meals.

Metformin HCl (500mg) is a biguanide that works by improving insulin sensitivity, reducing glucose production in the liver, and increasing glucose uptake in muscles. It is considered the first-line treatment for type 2 diabetes due to its effectiveness and low risk of causing hypoglycemia.

This combination is often prescribed when blood sugar control is insufficient with Metformin alone, or when a more potent blood sugar-lowering effect is needed. The two medications work together synergistically to improve glycemic control, and it is typically taken alongside a balanced diet and exercise plan.