The combination of Amlodipine Besylate (Eq. to Amlodipine 5mg) and Metoprolol Succinate (23.75mg/47.5mg, Eq. to Metoprolol Tartrate 25mg/50mg SR) in a bilayer tablet is used to treat hypertension (high blood pressure) and angina (chest pain), offering a convenient, combined approach to managing these conditions. Amlodipine, a calcium channel blocker, works by relaxing and widening blood vessels, which helps reduce blood pressure and improve blood flow. Metoprolol Succinate, a beta-blocker in its extended-release (SR) form, lowers heart rate and reduces the heart’s workload, further aiding in blood pressure control and preventing angina. The bilayer formulation allows for sustained-release of both medications, ensuring effective, long-lasting control of blood pressure and heart function with a once-daily dose. This combination is particularly useful for patients who need both blood pressure-lowering effects and heart rate management.